CNN) -- China's Zheng Jie and Russian Elena Dementieva stand in the way of another all--Williams women's singles final at Wimbledon on Saturday.
Zheng knows what is like to win a title at Wimbledon, after her 2006 doubles triumph.
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With the four top seeds all eliminated most people expect the two American sisters to fight out their third clash for the title this weekend.
They have dominated the tournament in recent years, with Venus winning the title in 2000, 2001, 2005 and 2007 and Serena taking the trophy - by beating her sister -- in 2002 and 2003.
Venus, who will play Dementieva in the semifinals, insisted: "It doesn't matter who's in the tournament or not. It doesn't play a factor in how we feel about ourselves.
"It's nice to be favorite, that's for sure. But I'm going to go out there and work just as hard as if I was or if I wasn't the favorite."
Venus has beaten Dementieva in five of the pair's seven meetings although they have never played on grass.
Serena has won her only previous meeting with Zheng, the first Chinese player to get this far in a Grand Slam. That was at Wimbledon in 2006.
Serena said she had been impressed by Zheng's performances this year, which included the defeat of world number one and top seed Ana Ivanovic in the third round.
Lowly ranked Zheng needed a wildcard to get into the main draw but Serena said: "I've been watching her play. I think she's doing a fabulous job, and I don't think it's luck. I'm definitely not going to underestimate her."
Zheng has taken center stage at the All England Club before, having won the doubles with Yan Zi in 2006.
"It was very exciting to win in 2006, but also it was at the same time as the World Cup, so it was not received as sensationally in China as the football," Zheng said.
"But Wimbledon is a very historic tournament and there is a lot of affection for it in China."
Fifth seed Dementieva is the highest-ranked player left in the draw and is hoping to improve on her previous best Grand Slam performances when she was runner-up at the 2004 French and US Opens.
For all her unquestionable ability, Dementieva has sometimes looked vulnerable because of her temperament.
At the French Open this year, she let slip a set and 5-2 lead, as well as a match point, to lose to Dinara Safina.
Her victory over compatriot Nadia Petrova in Tuesday's quarterfinal almost went the same way.
She was a set and 5-1 ahead and wasted two match points before reasserting her superiority in the third set..
"Venus is the defending champion. She likes to play on grass. She really knows how to play here, so I think she's a favorite," said Dementieva, playing in her first Wimbledon semifinal.
"All the pressure's on her. I really have nothing to lose."
If the sisters do battle out the final again Serena will be able to accept defeat more easily if the crown stays with defending champion Venus.
"It definitely hurts less to lose to her. I'll be bitter, but at the end of the day it's a lot easier than losing to someone that I feel I should normally beat," Serena said.
They have contested five Grand Slam finals in all and Venus has triumphed only once.
"I would never sit here and say she's the favorite when I'm still in the draw," Serena said.
" I always believe that I'm the favorite. Even if I'm not the favorite, I'm always going to believe that I am.
"I'm definitely more expressive with my competitive spirit. Venus is definitely competitive, but more low key, where I'm more out there.
"It's kind of always been like that. She's always been a little more quiet and I've been a little more outgoing personality wise."
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